Associate Professor Dr.Chalermchai Pilapong
Assistant Professor Dr. Chalermchai Pilapong, Ph.D Center of Excellence for Molecular Imaging and AMS Cancer Research Unit, Faculty of Associated Medical Sciences, Chiang Mai University, Thailand. Chalermchai Pilapong received his PhD degree in Chemistry from Chiang Mai University in 2012. Currently, Dr. Chalermchai Pilapong is an Assistant Professor in the Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University. His research interests focus on development of new potential nanobio-technology, nanomedicine and molecular imaging for the diagnosis and treatment of various diseases including cancers.
Book
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Communications
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Selected current projects
1. Atomic Magnetometer for Precision Measurements of Brain and Heart Magnetic Signals
2. Biocompatible tannin acid ; A molecular tool for imaging (MRI) and treatment of diseases associated with abnormal iron homeostasis
3. Development of Fe-tannic molecular nanoparticles for medical applications
4. Imaging of cancer stem cell and early metastatic cancer using EpCAM aptamer-fluorescent NPs conjugate
5. Development of targeted multimodal imaging agent in ionizing radiation-free approach for visualizing hepatocellular carcinoma
Research Interests
1. Develop various highly-sensitive Molecular probe which can be utilized for non-invasively imaging biological processes, cell tracking, early diagnosis, and monitoring of therapeutic efficacy.
2. Develop new therapeutic systems based on nano-hybrid /biomolecules.
3. Develop multifunctional theranostic agents that not only carry and deliver natural therapeutics agent or chemotherapeutics but also provide real-time imaging of therapy response in vivo.
4. Bimagnetic signal detection
5. Iron homeostasis in cancer
Research Patents
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Research Publications
1. C. Pilapong*, S. Siriwongnanon, Y. Keereeta, Development of targeted multimodal imaging agent in ionizing radiation-free approach for visualizing hepatocellular carcinoma cells, Sensors and actuators B: Chemical, 2017, 245, 683-694
2. S. Sittiichai, C. Pilapong*, T. Thongtem, S. Thongtem*, CMC-coated Fe3O4 nanoparticles as new MRI probes for hepatocellular carcinoma, Applied surface science, 2015, 356, 972-977
3. C. Pilapong*, C. Raiputta, J. Chaisupa, S.Sittichai, S. Thongtem , T. Thongtem. Magnetic-EpCAM Nanoprobe as a New Platform for Efficient Targeting, Isolating and Imaging Hepatocellular Carcinoma, RSC Advance, 2015, 5, 30687.
4. Chalermchai Pilapong*, Siwatt Pongpiajun, Samlee Mankhetkorn, Visualizing reactive oxygen species inside cancer cells after stimulation with polycyclic aromatic hydrocarbon via spontaneous formation of Au nanoclusters, Material Letter, 2015, 140, 162-165.
5. Chalermchai Pilapong*, Sudarat Sitthichai, Somchai Thongtem, Titipun Thongtem, Smart Magnetic Nanoparticle-Aptamer Probe for Targeted Imaging and Treatment of Hepatocellular Carcinoma, International Journal of Pharmaceutics , 2014, 473, 469-474.
6. Chalermchai Pilapong*, Yanee keereeta, Samlee Munkhetkron, Somchai Thongtem, Titipun Thongtem, Enhanced Doxorubicin Delivery and Cytotoxicity in Multidrug Resistant Cancer Cells Using Multifunctional Magnetic Nanoparticles, Colloids and Surfaces B: Biointerfaces, 2014, 113, 249-253.
7. Yue Zhang, Chalermchai Pilapong, Yuan Guo, Zhenlian Ling, Oscar Cespedes, Philip Quirke, and Dejian Zhou*, Sensitive, Label-free Quantitation of Multiple DNA Targets Using a Magnetic Nanoparticle-Enzyme Sandwich Assay, Analytical Chemistry, 2013, 85, 9238-44
Research and professional experiences
2016-2017 :
Principle Investigator (PI) of research project entitled Development of Fe-Tannic Molecular nanoparticles for medical applications (supported by National Research Council of Thailand)
2015-2017 :
Principle Investigator (PI) of research project entitled "Development of targeted multimodal imaging agent in ionizing radiation-free approach for visualizing hepatocellular carcinoma" (TRF Grant for New research)
2015-2016 :
Principle Investigator (PI) of research project entitled Potential of tannic acid as natural iron chelator and molecular imaging agent for MRI (supported by National Research Council of Thailand)
2015 :
Junior Research Fellowship (In vivo imaging of metastatic cancer using EpCAM-fluorescent nanoparticle) supported by The Embassy of France
2013-2014 :
Principle Investigator (PI) of research project entitled Development of magnetic nanoparticle for specified MRI imaging of liver cancer (National Research University, NRU project)
2013-2014 :
Principle Investigator (PI) of research project entitled Treatment of drug-sensitive and Multidrug-resistant cancer cells using multifunctional nanoparticles (CMU young researcher)
2013-2014 :
Post-doctoral research (Mechanism of PAHs mediated cytotoxic against hepatocyte infected with hepatitis B virus and hepatocellular carcinoma cells)